A 50 year old female came to the OPD with the chief complaints of pain and stiffness in several joints since 2 months
HISTORY OF PRESENT ILLNESS :
She was apparently asymptomatic 10 years ago, then she developed a dull aching type of pain and stiffness in her joints of the fingers (MCP joints) of right hand with limitation of movements at the joints. 
Then within 5 months of onset of the disease, it progressed to involve other joints of the right hand and left hand as well ( wrist joint and elbow joint ) 
Within 5 years of onset she started feeling pain in the joints of the feet and ankle. 
Since 2 months the pain became unbearable  limiting  her activities. 
The pain was insidious in onset, slowly progressive dull aching type of pain, non radiating,aggravated by rest and relieved on activity and associated with swelling, stiffness and limitations of movements in the involved joints.
Stiffness and pain was more in the first 1 hour of waking up and gradually improved on movement.
There are few exacerbations associated with intermittent fever.
No deformities 
No loss of weight.
PAST HISTORY :
She has no similar complaints 10 years ago. 
No history of thyroid, asthma, hypertension, diabetes. 
DRUG HISTORY :
No known drug allergies 
MENSTRUAL HISTORY :
Menarch: 13 years 
Regular, 29 day cycles 
Menopause: 47 years 
FAMILY HISTORY :
No similar complaints
PERSONAL HISTORY :
Diet: mixed 
Appetite: normal 
Bowel and bladder: regular 
Sleep: adequate 
GENERAL EXAMINATION :
patient is conscious coherent and cooperative 
Moderately built and nourished 
No edema
No icterus 
No cyanosis 
No lymphadenopathy 
No pallor 
VITALS:
Temperature: afebrile 
Blood pressure: 115/70mmHg
Respiratory rate: 15cpm
Pulse rate: 72bpm
LOCAL EXAMINATION :
INSPECTION :
Skin : 
No pigmentation 
No scars 
No atrophic changes 
Nails: normal 
Soft tissues: mild swelling over the joints 
Deformities : no deformities 
PALPATION :
Skin: warm
Sensations are preserved 
Soft tissues: no edema 
Joint capsule: mild swelling over the joint 
Tenderness over the joint (squeeze test)
Movements: 
Decreased range of movements at PIP, MCP, wrist, elbow, ankle joints 
All active and passive movements at the involved joints are painful .
Extra articular manifestations :No lymphadenopathy 
SYSTEMIC EXAMINATION :
CARDIOVASCULAR SYSTEM
Apex beat:  5th intercostal space located near the midclavicular line 
S1 and S2 heard 
JVP NORMAL 
Pedal edema : absent 
RESPIRATORY SYSTEM
Breath sounds: normal 
No additional breath sounds 
CENTRAL NERVOUS SYSTEM
Gait: normal 
cranial nerves intact 
Reflexes preserved
Sensations preserved 
Joint position sense: intact 
ABDOMEN
No abnormal findings found
DIFFERENTIAL DIAGNOSIS
1. Osteoarthritis 
2. Rheumatoid arthritis 
INVESTIGATIONS:
1. Complete blood picture 
2. ESR 
3. CRP
4. Rheumatoid factor 
5. Antibodies
6. Renal function tests 
7. Urine examination 
8.  Liver function tests
9. X-ray
PROVISIONAL DIAGNOSIS:
                                                
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